OpenPedCan-analysis

Scripts exclusively for publication-ready plots

We list information about the relevant figures and modules for each script in this directory below for convenience.

Individual script Figure(s) Linked analysis modules
fig1-sample-distribution.R Figure 1B N/A
fig2_figS3-oncoprint-landscape.R Figure 2 & Figure S3B oncoprint-landscape
fig3-chromothripsis-barplot.R Figure 3D chromothripsis
fig3_figS4-mutational-signatures-panels.R Figure 3E and Figure S4 mutational-signatures
fig4-tp53-telomerase-panels.R Figure 4 panels A, B, C, D, F tp53_nf1_score
telomerase-activity-prediction
survival-analysis
fig4-heatmap.R Figure 4E mutational-signatures
fig4-hgg-kaplan-meier.R Figure 4H survival-analysis
fig4-hgg-subtype-forest-plot.R Figure 4G survival-analysis
fig5-panels-gsva-umap.R Figure 5 panels A, B transcriptomic-dimension-reduction
collapse-rnaseq
gene-set-enrichment-analysis
fig5-forest-plot.R Figure 5D survival-analysis
immune-deconv
fig5_figS6-immune-deconv-panels.R Figure 5 panels C, E and Figure S6 panels E, F immune-deconv
figS2-snv-callers-panels.R Figure S2 panels A-G snv-callers (:warning: Requires 32 GB RAM)
figS2-tmb-compare-panels.R Figure S2 panels H, I tmb-compare
figS3-panels-cn-chromothripsis.R Figure S3 panels C, D, E cnv-chrom-plot
chromothripsis
copy_number_consensus_call
figS5-all-panels.R Figure S5 A-C tp53_nf1_score
telomerase-activity-prediction
figS6-subtype-umap-panels.R Figure S6 panels A-D transcriptomic-dimension-reduction
figS7-seqcenter-barplot.R Figure S7 panel A None
figS7-UMAP-libraries.R Figure S7 panel B None
figS7-tp53-telomerase-tumor-purity-threshold.R Figure S7 panel G transcriptomic-dimension-reduction
telomerase-activity-prediction
tumor-purity-exploration